Why use aptamers from all the ones available ligands?

We already saw that there were a few ligands available, and those were just to give an example of the different ligands that could be used during the process of development of Custom Chromatography Resin. But then, why use aptamers? Well, this is mostly because of the advantages it has.

Advantages

  • High Selectivity

  • Non-toxic/Non-immunogenic
     

  • Easily Prepared In Bulk

  • Stable in RT
     

  • Chemically Synthesized
     

  • Reduced Development Cost and Cycle Time